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For questions related to guppies - popular, polymorphic, live-bearing, tropical aquarium fish characterized by remarkably visible sexual dimorphism. Please include other tags relevant to the issue, such as [health] or [feeding].
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Does medicating an entire tank harm healthy fish?
As you've already pointed out, the best course of action is to quarantine the fish. If you really can't do this then you'll need to tread carefully with medicines if you have any invertebrates (snails …