I have a 2 year old neutered male house cat. Had him since he was 10 weeks old.
He has never liked being picked up - no matter how gently we do it. He does not like being petted very often either, and if you do, after 2-3 times, he bites you very hard.
I scold him but never hit him when he does that, just leave him alone. He almost never will sit on my lap.
He does follow me around the house a lot. He gets toys, treats, very good soft and dry food, fresh cold water daily.
He never lets me hold him for more than a minute, except when he is at the vets, and I'm sure that is because he is terrified!
I love him, talk to him, and my husband and I play with him with his toys. We have never let him outdoors. I was thinking if we did occasionally would he be less aggressive and happier? But we live in the country and scared he could get hurt, etc.