i'mI'm very sorry for you and your cat. My cat (around 15-16 years old) is also havinghas a calicivirus infection, for several years now. He was treated with ARA 3000 ALPHA duringfor 2 years and it helped a lot. The treatment is a bit difficult to put in place, as the patient needs an injection every 3 days during the first 2 or 3 weeks, then it is once a month, but it worked quite well. We then started a new treatment with laserlasers (no tranquilization needed, my cat understood quite fast that the treatment is good for him). During a year my cat had both ARA and laser once a month. Now he is "only" having laser when he needs (more or less once a month). I also put an aloevera gel (called Buccanima) in his mouth once a day, it seems to help with the pain. I hope this can help, as I'm living in France and I do not know if you can have access to these treatments. Good luck and my best wishes.