If you are doing aquaponics and you have to clean your tank, you are not doing it right. You should have an ammonia and nitrogen cycle going. I have two ponds, one on the top of my hillside and one on the bottom. I've had a permaculture food forest going for about 7 years now. I have a couple different species of fish in the top larger pond. That pond filters down through my Swales until it feeds into my smaller pond at the bottom of the hillside where I have shrimp, red claws ("freshwater lobster") and feeder fish.
I live in a Southern California and have found it possible to create different microclimates on my land. I recently just started my symbotic relationship between ducks and rice. I got to say it's going great, the ducks eat all the weeds and provide nutrients for the rice. Not to mention they are ready to be sold or harvested by the time the rice is harvested.
Anyway to the main question: no, you cannot. You would be better off having two or three ponds, especially if you want to start a homestead. Those ponds can also be used to water plants near by or for your animals to drink.
When building a homestead/permaculture everything should have more than one use in my opinion. I have a small, 3 acre farm that's done wonders. 40 chickens give me more eggs than I could ever ask for, kill bugs and turn over my topsoil. 30 ducks feed my rice field, while my rice field feeds my ducks. My fish pond feeds my nut trees, berries, fruits, veggies, spices, etc. while my crustacean pond feeds my herbs, leafy greens and water loving cukes and melons. I recently just got 6 pigs that I let roam free in my 1/2 acre of woods, where I have a bunch of nut and fruit trees planted. I'm hoping after they eat all the hazelnuts, acorns, apples, etc that fall on the ground that the flavor will be out of this world.